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Multiple Choice

Door-to-fibrinolytic time for treating acute myocardial infarction should be within how many minutes?

In acute myocardial infarction, every minute counts because myocardium at risk is salvaged with prompt reperfusion. The key idea is to minimize the door-to-needle time for fibrinolytic therapy—the time from the patient’s arrival to giving the fibrinolytic agent. The recommended target is 30 minutes or less. Starting fibrinolysis within 30 minutes of arrival optimizes survival, reduces infarct size, and lowers complications. Delays beyond 30 minutes lessen the benefit and are associated with worse outcomes, so the options that imply longer timeframes (60, 90, or 120 minutes) are not aligned with best practice for fibrinolysis.

In acute myocardial infarction, every minute counts because myocardium at risk is salvaged with prompt reperfusion. The key idea is to minimize the door-to-needle time for fibrinolytic therapy—the time from the patient’s arrival to giving the fibrinolytic agent. The recommended target is 30 minutes or less. Starting fibrinolysis within 30 minutes of arrival optimizes survival, reduces infarct size, and lowers complications. Delays beyond 30 minutes lessen the benefit and are associated with worse outcomes, so the options that imply longer timeframes (60, 90, or 120 minutes) are not aligned with best practice for fibrinolysis.