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Multiple Choice

For outpatient nonpurulent cellulitis, which pathogen is most commonly implicated?

Nonpurulent cellulitis in outpatients is most often caused by beta-hemolytic streptococci, with Streptococcus pyogenes (Group A Streptococcus) being the leading pathogen. The hallmark is diffuse, warm, tender erythema without pus or abscess formation, which fits a streptococcal pattern rather than a purulent Staphylococcus aureus infection. When there is purulence or abscess, Staph aureus becomes more likely, including MRSA in some settings. Pseudomonas and E. coli are not typical culprits for uncomplicated nonpurulent cellulitis unless there are specific risk factors or unusual presentation.

Nonpurulent cellulitis in outpatients is most often caused by beta-hemolytic streptococci, with Streptococcus pyogenes (Group A Streptococcus) being the leading pathogen. The hallmark is diffuse, warm, tender erythema without pus or abscess formation, which fits a streptococcal pattern rather than a purulent Staphylococcus aureus infection. When there is purulence or abscess, Staph aureus becomes more likely, including MRSA in some settings. Pseudomonas and E. coli are not typical culprits for uncomplicated nonpurulent cellulitis unless there are specific risk factors or unusual presentation.