How does Hodgkin's lymphoma typically spread through the lymphatic system?

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Multiple Choice

How does Hodgkin's lymphoma typically spread through the lymphatic system?

Hodgkin lymphoma spreads in an orderly, contiguous fashion through the lymphatic system, moving from one lymph node group to the next along the normal drainage pathways. This means initial involvement is usually in a single nodal region (often cervical or mediastinal) with progression to adjacent nodal groups on the same side of the diaphragm before reaching more distant sites. Hematogenous spread to the liver tends to occur later in more advanced disease, while noncontiguous (skip) spread and transcoelomic spread are not typical patterns for Hodgkin lymphoma.

Hodgkin lymphoma spreads in an orderly, contiguous fashion through the lymphatic system, moving from one lymph node group to the next along the normal drainage pathways. This means initial involvement is usually in a single nodal region (often cervical or mediastinal) with progression to adjacent nodal groups on the same side of the diaphragm before reaching more distant sites. Hematogenous spread to the liver tends to occur later in more advanced disease, while noncontiguous (skip) spread and transcoelomic spread are not typical patterns for Hodgkin lymphoma.

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