In SIADH, which urine characteristic is typically observed?

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Multiple Choice

In SIADH, which urine characteristic is typically observed?

In SIADH, there is inappropriately elevated ADH which causes the kidneys to reabsorb free water. This leads to hyponatremia with a euvolemic state. Because water is being reabsorbed, the urine becomes highly concentrated. The hallmark finding is a urine osmolality that is elevated, typically greater than 100 mOsm/kg (often much higher). Urine sodium is also usually high due to natriuresis, and urine output is usually normal or even increased, as the body tries to excrete excess salt to maintain euvolemia. A urine volume that is decreased is not typical in SIADH. So the best characteristic is high urine osmolality.

In SIADH, there is inappropriately elevated ADH which causes the kidneys to reabsorb free water. This leads to hyponatremia with a euvolemic state. Because water is being reabsorbed, the urine becomes highly concentrated. The hallmark finding is a urine osmolality that is elevated, typically greater than 100 mOsm/kg (often much higher). Urine sodium is also usually high due to natriuresis, and urine output is usually normal or even increased, as the body tries to excrete excess salt to maintain euvolemia. A urine volume that is decreased is not typical in SIADH. So the best characteristic is high urine osmolality.

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