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Multiple Choice

Lymphoma diagnosis/staging: Which statement defines Stage II?

Stage II involves involvement of two or more lymph node regions on the same side of the diaphragm, with or without nearby extranodal organ involvement, but not across both sides of the diaphragm. This distinguishes it from Stage I, which is limited to a single lymph node region; from Stage III, which requires nodal involvement on both sides of the diaphragm (often with spleen involvement); and from Stage IV, which denotes disseminated disease such as liver or bone marrow involvement. So describing multiple lymph node regions on one side of the diaphragm best fits Stage II.

Stage II involves involvement of two or more lymph node regions on the same side of the diaphragm, with or without nearby extranodal organ involvement, but not across both sides of the diaphragm. This distinguishes it from Stage I, which is limited to a single lymph node region; from Stage III, which requires nodal involvement on both sides of the diaphragm (often with spleen involvement); and from Stage IV, which denotes disseminated disease such as liver or bone marrow involvement. So describing multiple lymph node regions on one side of the diaphragm best fits Stage II.