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Multiple Choice

Mitral regurgitation may present with which of the following signs?

Mitral regurgitation causes volume overload of the left ventricle as blood leaks back into the LV during systole. That extra volume stretches the ventricle and commonly produces a third heart sound (S3) in early diastole, reflecting rapid passive filling into a dilated, overloaded ventricle. An S4, by contrast, signals a noncompliant, stiff ventricle and is more typical of long-standing hypertension or hypertrophic changes. An opening snap is characteristic of mitral stenosis, not MR, and a pericardial rub points to pericarditis. So the sign most aligned with MR is an S3.

Mitral regurgitation causes volume overload of the left ventricle as blood leaks back into the LV during systole. That extra volume stretches the ventricle and commonly produces a third heart sound (S3) in early diastole, reflecting rapid passive filling into a dilated, overloaded ventricle. An S4, by contrast, signals a noncompliant, stiff ventricle and is more typical of long-standing hypertension or hypertrophic changes. An opening snap is characteristic of mitral stenosis, not MR, and a pericardial rub points to pericarditis. So the sign most aligned with MR is an S3.