Regarding prognosis of ALL, which statement is true?

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Multiple Choice

Regarding prognosis of ALL, which statement is true?

Prognosis for acute lymphoblastic leukemia varies greatly by age. Children respond very well to current multiagent chemotherapy regimens, with remission achieved in the vast majority and cure possible in about 90% of cases. In adults, however, remission and cure rates are substantially lower, and outcomes are worse due to factors like different disease biology, higher-risk cytogenetics, and greater treatment intolerance. Therefore, the statement that it is more difficult to cure in adults, with about 90% remission in children, is the accurate reflection of prognosis. Lymphocytosis is not a defining or typical presenting feature of ALL; presentations are more related to bone marrow failure symptoms and variable white cell counts.

Prognosis for acute lymphoblastic leukemia varies greatly by age. Children respond very well to current multiagent chemotherapy regimens, with remission achieved in the vast majority and cure possible in about 90% of cases. In adults, however, remission and cure rates are substantially lower, and outcomes are worse due to factors like different disease biology, higher-risk cytogenetics, and greater treatment intolerance. Therefore, the statement that it is more difficult to cure in adults, with about 90% remission in children, is the accurate reflection of prognosis. Lymphocytosis is not a defining or typical presenting feature of ALL; presentations are more related to bone marrow failure symptoms and variable white cell counts.

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