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Multiple Choice

TB skin test induration of 5 mm is considered positive in which individuals?

The test uses the size of the induration to decide positivity, and the cutoff depends on risk. In people with HIV infection or known TB infection (or other severely immunocompromised states), a smaller induration is considered positive because their immune response can be reduced, so 5 mm or more signifies infection. In those with some TB risk factors but not severely immunocompromised, larger cutoffs are used (typically 10 mm), and in people with no risk factors, 15 mm or more is the threshold. So a 5 mm induration is positive specifically in individuals with HIV or known TB infection.

The test uses the size of the induration to decide positivity, and the cutoff depends on risk. In people with HIV infection or known TB infection (or other severely immunocompromised states), a smaller induration is considered positive because their immune response can be reduced, so 5 mm or more signifies infection. In those with some TB risk factors but not severely immunocompromised, larger cutoffs are used (typically 10 mm), and in people with no risk factors, 15 mm or more is the threshold. So a 5 mm induration is positive specifically in individuals with HIV or known TB infection.