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Multiple Choice

What is the approximate 5-year survival rate for CML in affected patients?

In CML, prognosis depends on disease phase and response to targeted therapy. With modern treatment, especially tyrosine kinase inhibitors, many patients in the chronic phase live long, but when looking at all patients across all stages, the 5-year survival averages out to around the mid-60s percent. That's why about 65% is the best estimate for the overall 5-year survival. Numbers like 25% or 50% are lower than what many treated populations show, and 85% would be high for the broad all-stages population. Remember, survival is higher for those diagnosed in the chronic phase with good treatment response, and much lower for those with accelerated or blast-crisis.

In CML, prognosis depends on disease phase and response to targeted therapy. With modern treatment, especially tyrosine kinase inhibitors, many patients in the chronic phase live long, but when looking at all patients across all stages, the 5-year survival averages out to around the mid-60s percent. That's why about 65% is the best estimate for the overall 5-year survival. Numbers like 25% or 50% are lower than what many treated populations show, and 85% would be high for the broad all-stages population. Remember, survival is higher for those diagnosed in the chronic phase with good treatment response, and much lower for those with accelerated or blast-crisis.