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Multiple Choice

Which of the following findings is commonly seen on radiographs in rheumatoid arthritis?

Inflammatory destruction of joint surfaces in rheumatoid arthritis leads to loss of articular cartilage, so the space between bones narrows on radiographs. This joint-space narrowing is a hallmark of RA as pannus erodes cartilage over time. Other findings described are more characteristic of osteoarthritis or non-specific inflammatory changes: osteophytes and subchondral sclerosis point to degenerative OA, while juxta-articular sclerosis is not typical in RA (juxta-articular osteopenia is more common). Early RA may also show soft tissue swelling and marginal erosions, but the narrowing of the joint space consistently reflects cartilage loss from chronic inflammatory synovitis.

Inflammatory destruction of joint surfaces in rheumatoid arthritis leads to loss of articular cartilage, so the space between bones narrows on radiographs. This joint-space narrowing is a hallmark of RA as pannus erodes cartilage over time. Other findings described are more characteristic of osteoarthritis or non-specific inflammatory changes: osteophytes and subchondral sclerosis point to degenerative OA, while juxta-articular sclerosis is not typical in RA (juxta-articular osteopenia is more common). Early RA may also show soft tissue swelling and marginal erosions, but the narrowing of the joint space consistently reflects cartilage loss from chronic inflammatory synovitis.